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TCR-Vγδ usage distinguishes protumor from antitumor intestinal γδ T cell subsets.
Reis BS, Darcy PW, Khan IZ, Moon CS, Kornberg AE, Schneider VS, Alvarez Y, Eleso O, Zhu C, Schernthanner M, Lockhart A, Reed A, Bortolatto J, Castro TBR, Bilate AM, Grivennikov S, Han AS, Mucida D. Reis BS, et al. Among authors: darcy pw. Science. 2022 Jul 15;377(6603):276-284. doi: 10.1126/science.abj8695. Epub 2022 Jul 14. Science. 2022. PMID: 35857588 Free PMC article.
Intestinal tuft cell immune privilege enables norovirus persistence.
Strine MS, Fagerberg E, Darcy PW, Barrón GM, Filler RB, Alfajaro MM, D'Angelo-Gavrish N, Wang F, Graziano VR, Menasché BL, Damo M, Wang YT, Howitt MR, Lee S, Joshi NS, Mucida D, Wilen CB. Strine MS, et al. Among authors: darcy pw. Sci Immunol. 2024 Mar 22;9(93):eadi7038. doi: 10.1126/sciimmunol.adi7038. Epub 2024 Mar 22. Sci Immunol. 2024. PMID: 38517952
YY1lo NKT cells are dedicated IL-10 producers.
Darcy PW, Denzin LK, Sant'Angelo DB. Darcy PW, et al. Sci Rep. 2020 Mar 3;10(1):3897. doi: 10.1038/s41598-020-60229-6. Sci Rep. 2020. PMID: 32127556 Free PMC article.